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CELL CULTIVATION

Increase reproducibility and efficiency using next-gen science. 

Life Science

The Sphericalplate 5D (SP5D) is a 3D cell culture plate capable of producing up to 20,000 uniform and standardized spheroids in a single plate. These spheroids can be formulated in three easy steps and are suitable for various applications, including cancer and tumor biology, drug screening, radiosensitivity studies, tissue engineering, and neurodegenerative disease research. 

Heidolph | Kugelmeiers

Sphericalplate 5D

Hei-CELL

Patented micro-well geometry
Patented micro-well geometry
Pre-applied specialized coating. No additional buffers or reagents are needed. 
Pre-applied specialized coating. No additional buffers or reagents are needed. 
Uniform clustering
Uniform clustering

The Sphericalplate 5D (SP5D) is a 3D cell culture plate designed to produce uniform, standardized, size-controlled spheroids with high quality and yield. Effortlessly scale and translate your spheroids into various diagnostic or clinical applications. Increase the reproducibility of follow-up tests with experiments starting under identical conditions due to the low size variance of the cultivated spheroids. 

3D Cell Culture Plates

For those who prefer not to rely on the inefficient Hanging Drop Method for spheroid cultivation, using specially designed 3D cell culture plates is essential. When selecting the appropriate plate, several factors should be considered to achieve the desired results. Key points to consider include handling, coating, and scalability. This Buyer's Guide will help you identify the most important aspects of choosing the right 3D cell culture plate for your application. 

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What are 3D Cell Cultures and how do they work?

Cell culture research is the basis of biological research. Animal cells serve as a cornerstone for various studies and for examining the effects of new medicines on cells. This can significantly reduce the need for animal testing. Different approaches can be used in cell culture. In 2D cell culture, animal cells are either cultivated in suspension culture (free-floating in the medium) or as adherent cells (forming a monolayer on a surface). However, 2D cell culture has limitations, particularly in terms of cell interactions. To overcome these limitations, 3D cell cultures can be used. The concept behind 3D cell cultures is straightforward; since the world and all organisms are three-dimensional, it makes sense to apply this structure to cell culture as well. 

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